The following people are credited as replacements or additions if they were not credited on opening night.

Assistant Director: Eileen F. Haggerty.

Assistant Costume Design: Michael Hannah; Assistant Lighting Design: Michael P. Jones.

Company Manager: Doug Gaeta; Assistant Co. Mgr: Tammie Ward.

Second Assistant Stage Manager: Andrew Neal; Production Stage Manager: Kathleen E. Purvis; Stage Manager: Andrew Neal; Assistant Stage Mgr: Jim Athens, Valerie Lau-Kee Lai.

Dance Captain: Natalie Lomonte; Advertising: AKA; Marketing: AKA; Assistant Dance Captain: Drew Heflin; Dance Captain: Dana Marie Ingraham.

Ashley Adamek	Ensemble	(Jul 24, 2012 - ?)
	Aerialist
Stephen Lee Anderson	Buttons A Reporter
	Ensemble
	Uncle Ben
	Viper Executive
David Armstrong	Aerialist
	Ensemble
	Exterminator Flyer
Gerald Avery	Ensemble	(May 22, 2012 - ?)
	Swarm One of the Sinister Six	(May 22, 2012 - ?)
Collin Baja	Carnage One of the Sinister Six
	Ensemble
Hettie Vyrine Barnhill	Ensemble	(Aug 21, 2012 - ?)
	Ring Girl	(Aug 21, 2012 - ?)
Emmanuel Brown	Kraven the Hunter One of the Sinister Six
Jessica Leigh Brown	Aerialist
Matt Caplan	Peter Parker/Spider-Man	Alternate
	Newsboy
Julius C. Carter	Aerialist
	Ensemble
	Purse Snatcher
	The Lizard One of the Sinister Six
Daniel Case	Aerialist
Cass Christopher	Ensemble
Robert Cuccioli	Norman Osborn/The Green Goblin	(Aug 7, 2012 - ?)
Christina DeCicco	Arachne	(Apr 23, 2013 - ?)
Mat Devine	Grim Hunter	Role was cut during previews
Adam Ray Dyer	Aerialist
Jake Epstein	Peter Parker/Spider-Man	Alternate
	Peter Parker/Spider-Man	Alternate
Rebecca Faulkenberry	Mary Jane Watson	(Nov 8, 2011 - ?)
Gideon Glick	Jimmy-6	Role was cut during previews
Drew Heflin	Aerialist
	Ensemble
	Swarm One of the Sinister Six
	Swarm One of the Sinister Six
Elizabeth Judd	Ensemble	(circa. Mar 20, 2012-Sep 16, 2012)
	Aerialist	(? - Sep 16, 2012)
Isabel Keating	Purse Lady
Reed Kelly	Aerialist
	Ensemble
	Swiss Miss One of the Sinister Six
Aaron LaVigne	A Gangster
	Ensemble
	Kong A Bully
	Travis A Reporter
	Viper Executive
Alice Lee	Miss Arrow	Role was cut during previews
Katrina Lenk	Arachne	(May 29, 2012-Apr 21, 2013)
Kourtni Lind	Ring Girl
	Aerialist
	Ensemble
Ken Marks	Buttons A Reporter
	Ensemble
	Uncle Ben
	Viper Executive
Kristin Martin	Ensemble
India McGee	Ensemble	(Jul 24, 2012 - ?)
Monette McKay	Ensemble
	Aerialist
Natalie Mendoza	Arachne	Was replaced in previews
Bethany Moore	Ring Girl
Jake Odmark	A Gangster
	Bud A Reporter
	Ensemble
	Flash A Bully
	Newsboy
Maxx Reed	Electro One of the Sinister Six	(Mar 20, 2012 - ?)
	Ensemble	(Mar 20, 2012 - ?)
Adam Roberts	Aerialist
	Carnage One of the Sinister Six
	Ensemble
	Green Goblin Flyer
	Swiss Miss One of the Sinister Six
Brandon Rubendall	Ensemble	(Aug 14, 2012 - ?)
	Swiss Miss One of the Sinister Six	(Aug 14, 2012 - ?)
Christina Sajous	Arachne	(Nov 15, 2011-May 27, 2012)
Josh Sassanella	Aerialist
Jonathan Schwartz	Professor Cobwell	Role was cut during previews
Dan Sharkey	Danny, Lab Assistant
	Ensemble
	Mary Jane's Father
	Ring Announcer
	Stokes A Reporter
	Viper Executive
Emily Shoolin	Emily Osborn
	Ensemble
	Marbles
	MJ's Friend
	Receptionist
	Emily Osborn
	Ensemble
	Marbles
	MJ's Friend
	Receptionist
Whitney Sprayberry	Ensemble	(Jul 3, 2012 - ?)
	Aerialist
Dollar Tan	Trainer
Cassandra Taylor	Aerialist	(Jun 28, 2011 - ?)
	Ensemble	(Jun 28, 2011 - ?)
Brett Thiele	Ensemble
	Trainer
Christopher Tierney	Exterminator Flyer
	Meeks A Bully
Timothy Warmen	Ensemble
	Mary Jane's Father
	Stokes A Reporter
	Viper Executive
	Danny, Lab Assistant
	Ring Announcer
	Danny, Lab Assistant
	Ensemble
	Mary Jane's Father
	Ring Announcer
	Stokes A Reporter
	Viper Executive
Laura Beth Wells	MJ's Friend
	Receptionist
	Emily Osborn	(Jun 19, 2012 - ?)
	Ensemble	(Jun 19, 2012 - ?)
	Marbles	(Jun 19, 2012 - ?)
	MJ's Friend	(Jun 19, 2012 - ?)
	Receptionist	(Jun 19, 2012 - ?)
	Emily Osborn
	Ensemble
	Marbles
	MJ's Friend
	Receptionist
	Emily Osborn
	Ensemble
	Marbles
	MJ's Friend
	Receptionist
Matthew Wilkas	A Gangster
	Bud A Reporter
	Ensemble
	Flash A Bully
	Newsboy

Swings: Jessica Leigh Brown, Daniel Case, Daniel Curry (, ), Adam Ray Dyer, Drew Heflin, Dana Marie Ingraham, Aaron LaVigne, Megan Lewis, Natalie Lomonte (, ), Kristin Martin, Paul McGill (, ), Jake Odmark, America Olivo, Jennifer Sanchez, Josh Sassanella, Jennifer Savelli, Jamison Scott, Joey Taranto.

Understudies: Stephen Lee Anderson (J. Jonah Jameson), David Armstrong (Electro), Kevin Aubin (Purse Snatcher, Trainer), Gerald Avery (Bud, Newsboy, A Gangster, Electro, Swarm, The Lizard, Trainer), Marcus Bellamy (Bud, Newsboy), Emmanuel Brown (Kong, Meeks), Jessica Leigh Brown (MJ's Friend, Purse Lady, Receptionist, Ring Girl), Matt Caplan (Viper Executive), Julius C. Carter (Boyle, Robertson), Luther Creek (Uncle Ben), Daniel Curry (A Gangster, Carnage, Kraven the Hunter, Swiss Miss, The Lizard), Adam Ray Dyer (A Gangster, Carnage, Electro, Kong, The Lizard, Trainer, Kraven the Hunter, Meeks, Purse Snatcher), Drew Heflin (Electro, Kraven the Hunter, Swarm, The Lizard, Trainer), Craig Henningsen (Kraven the Hunter), Dana Marie Ingraham (Purse Lady, Ring Girl, Swarm), Elizabeth Judd (Mary Jane Watson), Aaron LaVigne (A Gangster, Mary Jane's Father, Boyle, Bud, Buttons, Danny, Lab Assistant, Flash, Kong, Meeks, Newsboy, Ring Announcer, Robertson, Stokes, Travis, Viper Executive), Megan Lewis (MJ's Friend, Purse Lady, Receptionist), Ari Loeb (Carnage, Purse Snatcher, The Lizard, Trainer, Newsboy), Natalie Lomonte (Ring Girl, Purse Lady), Kevin Loomis (Bud, Robertson, Danny, Lab Assistant, Ring Announcer), Ken Marks (J. Jonah Jameson), Kristin Martin (Ring Girl, Mary Jane Watson), Paul McGill (A Gangster, Electro, Swarm, The Lizard, Trainer), Jake Odmark (A Gangster, Bud, Flash, Kong, Newsboy, Peter Parker/Spider-Man, Viper Executive, Travis), Kristen Oei (Mary Jane Watson), Kyle Post (Danny, Lab Assistant, Newsboy, Ring Announcer), Adam Roberts (Purse Snatcher, Swiss Miss), Brandon Rubendall (Carnage), Sean Samuels (Robertson, Viper Executive), Jennifer Sanchez (Arachne, Aunt May, Emily Osborn, Marbles, Maxie, MJ's Friend, Mrs. Gribrock, Purse Lady, Receptionist), Josh Sassanella (Purse Snatcher, A Gangster, Boyle, Bud, Flash, Kong, Meeks, Robertson, Travis, Viper Executive, Buttons, Danny, Lab Assistant, Kraven the Hunter, Newsboy, Ring Announcer, Stokes), Jamison Scott (A Gangster, Boyle, Bud, Flash, Kong, Meeks, Newsboy, Robertson, Travis, Viper Executive), Dan Sharkey (Norman Osborn/The Green Goblin, Uncle Ben), Emily Shoolin (Aunt May, Maxie, Mrs. Gribrock), Joey Taranto (Newsboy), Brett Thiele (Electro), Christopher Tierney (Flash), Timothy Warmen (Norman Osborn/The Green Goblin, Uncle Ben, J. Jonah Jameson, Buttons), Laura Beth Wells (Maxie, Aunt May, Mrs. Gribrock), Matthew Wilkas (Professor Cobwell, Viper Executive, Peter Parker/Spider-Man).