| Bob Amaral | Lycus a buyer and seller of courtesans | |
| Holly Cruikshank | Panacea a courtesan | |
| Kena Tangi Dorsey Broadway debut | Gymnasia a courtesan | |
| Pascale Faye | Vibrata a courtesan | |
| Gina Ferrall | Domina wife of Senex | |
| Robert Fitch | Senex a citizen of Rome | (? - Jan 4, 1998) |
| Whoopi Goldberg | Prologus an actor | |
| Pseudolus slave to Hero | ||
| David Alan Grier | Prologus an actor | |
| Pseudolus slave to Hero | ||
| Dick Latessa | Senex a citizen of Rome | |
| Ross Lehman | Hysterium slave to Senex and Domina | |
| Carol Lee Meadows | Vibrata a courtesan | |
| Tara Nicole | Geminae a courtesan, one of a pair | |
| Don Stitt | Lycus a buyer and seller of courtesans | (? - Jan 4, 1998) |
| Kristin Willits | Geminae a courtesan, one of a pair |