| 2013 Drama Desk Award Outstanding Musical Revue |
|---|
 | The Signature Theatre Company (James Houghton, Artistic Director; Erika Mallin, Executive Director) (for "Old Hats") [winner] |
| 2013 Drama Desk Award Outstanding Revival of a Play |
|---|
| | The Signature Theatre Company (James Houghton, Artistic Director; Erika Mallin, Executive Director) (for "The Piano Lesson") [nominee] |
| 2012 Drama Desk Award Outstanding Revival of a Play |
|---|
| | The Signature Theatre Company (James Houghton, Artistic Director; Erika Mallin, Executive Director) (for "The Lady from Dubuque") [nominee] |
| 2010 Drama Desk Award Special Award |
|---|
| The Signature Theatre Company (James Houghton, Artistic Director; Erika Mallin, Executive Director) (Saluting "the breadth of vision, which inspired the exceptional direction, performances, sets, lighting, costumes, music and sound that made ["The Orphans' Home Cycle"] the theatrical event of the season.") [winner] |
| 2006 Drama Desk Award Outstanding Revival of a Play |
|---|
| | The Signature Theatre Company (James Houghton, Artistic Director; Kathryn M. Lipuma, Executive Director) (for "The Trip to Bountiful") [nominee] |
| 2002 Drama Desk Award Outstanding New Play |
|---|
| | The Signature Theatre Company (James Houghton, Artistic Director; Bruce E. Whitacre, Managing Director) (for "Thief River") [nominee] |
| 1999 Drama Desk Award Outstanding Revival of a Play |
|---|
| | The Signature Theatre Company (James Houghton, Artistic Director; Bruce E. Whitacre, Managing Director) (for "Bosoms and Neglect") [nominee] |
| 1998 Drama Desk Award Outstanding Revival of a Play |
|---|
| | The Signature Theatre Company (James Houghton, Artistic Director; Thomas C. Proehl, Managing Director) (for "The American Clock") [nominee] |
| 1996 Drama Desk Award Honorary Award |
|---|
| The Signature Theatre Company (James Houghton, Artistic Director; Thomas C. Proehl, Managing Director) (for concept of annually serving one playwright) [winner] |
